Provera

What is Provera?

Provera is a treatment for irregular, heavy or painful periods. It contains the synthetic hormone called medroxyprogesterone. This hormone mimics the natural hormone found in the body called progesterone.

During a certain period, the levels of this hormone change, which affects the lining of the uterus. When progesterone levels are high, the lining of the uterus, also known as the endometrium, becomes more viscous, providing the appropriate conditions for an egg to implant itself, ready for fertilisation. When fertilisation does not happen, the endometrium is shed through period bleeding.

To help with this process, contractions occur within the muscles surrounding the womb. These contractions restrict the flow of oxygenated blood, which causes the body to release pain-triggering chemicals called prostaglandins.

The active ingredient of Provera is molecularly similar to progesterone and is typically prescribed when norethisterone is not suitable. Medroxyprogesterone sustains the endometrium and maintains the condition of the womb as if fertilisation has occurred. In turn, the body does not try to expel the lining from the womb by contracting the surrounding muscles.

How to take Provera?

Always take Provera as prescribed by your doctor. Do not exceed the prescribed dosage.

For heavy, irregular or painful periods, a typical dose would be between 2.5mg to 10mg for 5 to 10 days, beginning 16 to 21 days after your last period began. Your doctor may prescribe an oestrogen to take alongside Provera. You should experience breakthrough bleeding a few days after stopping the tablets.

If you miss a dose, do not take a double dose of Provera to make up for the missed dose. If you take more Provera than prescribed, speak to a doctor or pharmacist.

Provera tablets can be taken with or without food. You should swallow the tablets whole with a glass of water.

Provera side effects and cautions

All medications carry the risk of side effects, though not everyone will experience them. It’s important to understand the risks associated with taking the medication you are prescribed. A full list of side effects and contraindications can be found within the patient information leaflet, which comes enclosed with your medication.

Possible side effects of Provera include:

• Acne
• Breast tenderness or pain
• Depression
• Difficulty sleeping
• Dizziness
• Fever
• Hair loss
• Headache
• Nausea
• Rash or hives
• Tiredness
• Unexpected vaginal bleeding or spotting
• Vaginal discharge
• Weight change

This is not an exhaustive list of side effects. Further information regarding the safety of Provera can be found in the patient information leaflet enclosed with the product packaging.

Allergic reaction

Do not take Provera if you are allergic to Medroxyprogesterone or any of the other excipients of this medication.

Signs of an allergic reaction include:

• Difficulty breathing
• Dry, red, and cracked skin
• Itchy, red, watery eyes
• Raised, itchy, red rash (hives)
• Swelling of the face, lips, tongue or throat

If you experience signs of an allergic reaction, stop taking Provera and seek medical attention immediately.

Contraindications

Provera may not be suitable if you:

• Have Systemic Lupus Erythematosus
• Have asthma
• Have diabetes
• Have epilepsy
• Have hearing problems
• Have migraines
• Have or have had depression
• Have problems with your heart, liver or kidneys

Provera contains lactose and may not be suitable if you are lactose intolerant.

Pregnancy and breastfeeding

Do not take Provera if you are pregnant. If you are breastfeeding, speak to a doctor or pharmacist for an alternative method of feeding your baby while taking Provera.

Other safety information

Always seek your doctor’s advice before you buy Provera online.

Do not take Provera past the expiry date printed on the packaging. The date refers to the last do of that month.

Never discard medication via household or water waste. Take any unwanted or expired medicine to your pharmacy and ask them to dispose of it safely on your behalf.

Always keep medicine out of the sight and reach of children and pets.

Never share your medicine with someone else, even if they are experiencing the same symptoms as you.

Frequently asked questions