Liothyronine Sodium Injection 10 mcg/ 1 mL Single Dose Vial (RX)

Liothyronine Sodium for Injection (T3) Thyroid Hormone Agent 1mL by X-Gen Pharmaceuticals is a treatment of myxedema coma / precoma.

Each mL of liothyronine sodium injection (T3) in amber glass vials  contains,  in  sterile  non-pyrogenic  aqueous  solution,  liothyronine  sodium  equivalent  to  10  mcg  of  liothyronine;  alcohol, 6.8% by volume; anhydrous citric acid, 0.175 mg; ammonia,  2.19  mg,  as  ammonium  hydroxide; Water for injection, USP.

Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) sodium or triiodothyronine (T3, liothyronine) sodium or both. T4 and T3
are produced in the human thyroid gland by the iodination and  coupling  of  the  amino  acid  tyrosine.  T4  contains  four  iodine  atoms  and  is  formed  by  the  coupling  of  two  molecules  of  diiodotyrosine  (DIT).  T3 contains  three  atoms  of  iodine  and  is  formed  by  the  coupling  of  one  molecule  of  DIT  with  one  molecule  of  monoiodotyrosine  (MIT).  Both  hormones are stored in the thyroid colloid as thyroglobulin and released into the circulation. The major source of T3
has been shown to be peripheral deiodination of T4. T3 is bound less  firmly  than  T4  in  the  serum,  enters  peripheral  tissues  more  readily,  and  binds  to  specific  nuclear  receptor(s)  to  initiate  hormonal,  metabolic  effects.  T4 is  the  prohormone which is deiodinated to T3 for hormone activity.

Each Vial Contains:

• Liothyronine Sodium equivalent to 10 mcg of Liothyronine
• alcohol, 6.8% by volume
• anhydrous citric acid, 0.175 mg
• ammonia, 2.19 mg, as ammonium hydroxide
• Water for Injection, USP.

Brand: X-Gen Pharmaceuticals
Size: 1 mL Vial (1)
NDC: 39822-0151-1
UPC: 039822015114

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